Description
Product Description
Methylene Blue has long been studied for its ability to support mitochondrial ATP production, enhance memory and focus, and protect brain cells from oxidative and inflammatory damage. Users report increased mental clarity and mood, reduced brain fog, and improved alertness. Its unique mechanisms of action make it one of the few compounds with both metabolic and neuroprotective potential.
Methylene Blue offers flexible and precise dosing ideal for nootropic protocols, research use, or as part of anti-aging supplementation regimens.
Key Benefits:
Enhances mental clarity, focus, and memory
Supports mitochondrial ATP production
Promotes oxygen utilisation and blood flow to the brain
Reduces brain fog and may improve mood and focus
Provides cellular protection against oxidative stress
Investigated for anti-aging and neuroprotective applications
Product Information
Product Name: Methylene Blue, Methylthioninium Chloride
Molecular Formula: C₁₆H₁₈ClN₃S
Molecular Weight: 319.85 g/mol (as chloride salt)
CAS Number: 61-73-4
Synonyms: Methylthioninium chloride
What is Methylene Blue?
Methylene Blue is a synthetic compound originally developed as a dye, later adopted into medical and research use due to its biochemical activity at the mitochondrial level. It acts as an electron carrier within cells, facilitating efficient energy production (ATP) while reducing oxidative damage. Its applications span from brain health and cognition to potential anti-aging support.
Unlike many nootropics, Methylene Blue supports fundamental cell energy processes, making it a unique option for long-term cognitive performance and cellular vitality. Its mood-enhancing and memory-supporting effects have gained increasing interest in biohacking and research communities.
Mechanism of Action
Methylene Blue acts as an alternative electron carrier in the mitochondrial electron transport chain, bypassing damaged components and enhancing the efficiency of ATP production. This supports better energy output in high-demand cells, such as neurons, leading to improved cognitive performance and mental stamina.
It also inhibits nitric oxide synthase and guanylate cyclase, helping to modulate inflammatory processes and reduce oxidative stress. By limiting the production of nitric oxide and downstream reactive species, Methylene Blue contributes to neuroprotection and enhanced cellular resilience.
Furthermore, it helps reduce the generation of reactive oxygen species (ROS), preventing oxidative damage to proteins, DNA, and lipids. Preliminary research suggests that it may also affect monoamine oxidase (MAO) activity, influencing neurotransmitter levels involved in mood and alertness.
These mechanisms work together to position Methylene Blue as a powerful agent in supporting brain health, especially in aging populations or individuals facing cognitive fatigue or oxidative stress.
Dosing Protocol
Solution Concentration: 1.3% Methylene Blue
Content per mL: 13 mg
Suggested Microdose Range: 0.5 mg – 4 mg/day
Dosing Guideline: 0.05–0.1 mg/kg of body weight
Methylene Blue follows a biphasic dose-response curve (U-shaped), meaning excessive dosing may reduce its efficacy or increase risk of side effects. Lower doses often yield better nootropic results.
Cycle Guidelines
- Recommended Duration: 4–8 weeks on, followed by 2–4 weeks off
- Typical Starting Dose: 1 mg/day
- Maximum Daily Dose: Avoid exceeding 5 mg/day unless under clinical supervision
Due to its potent cellular effects and interaction with metabolic pathways, dosing should be approached cautiously, particularly in those taking SSRIs or with underlying health conditions.
Conclusions
Methylene Blue is a powerful compound with wide-reaching effects on cognitive function, mitochondrial energy, and cellular defense. With benefits reported in mood, focus, and neurological protection, it’s a promising addition to performance-enhancing and longevity-focused protocols.
Its antioxidant and anti-inflammatory properties have made it a candidate for further clinical research in age-related cognitive decline, brain fog, and neurodegeneration. For nootropic users and researchers alike, Methylene Blue offers a rare combination of efficacy, safety (at low doses), and versatility.
Buy Methylene Blue at Platinum Research Compounds
When you buy Methylene Blue in Australia from Platinum Research Compounds, you’re selecting a product backed by pharmaceutical-grade quality and tested for research-grade purity. Our commitment to research integrity, customer satisfaction, and rigorous quality control ensures your compound performs as intended.
Platinum Research Compounds is dedicated to supporting your scientific, research, or wellness objectives with expert service and reliable supply of high-purity Methylene Blue solution.
Product FAQ
What is Methylene Blue?
Methylene Blue is a synthetic compound with antioxidant and mitochondrial-supporting properties. It is used in medical and research settings for its ability to improve energy production, modulate oxidative stress, and enhance cognitive function.
What are the benefits of Methylene Blue?
It may improve focus, memory, and mood while protecting brain cells from aging and inflammation. It enhances mitochondrial efficiency and supports overall brain oxygenation and blood flow.
How does it work?
It acts as an alternative electron carrier in the mitochondrial electron transport chain, reducing reactive oxygen species and boosting ATP output. It may also influence brain chemistry via modulation of MAO enzymes and nitric oxide pathways.
How is it dosed?
Typically taken in microdoses between 0.5 mg and 4 mg daily, based on body weight (~0.05–0.1 mg/kg/day). Methylene Blue is most often administered orally or sublingually in liquid solution form.
Are there any precautions?
Yes. Due to its biphasic dose-response, higher doses may reduce its effectiveness or introduce risk. It may also interact with certain medications (especially SSRIs) and should be used under guidance if combined with other treatments.
What’s the best way to store Methylene Blue?
Keep refrigerated (2°C to 8°C) after opening, in a tightly sealed, UV-protective container.
