Description
Product Description
MOTS-C is a mitochondrial-derived peptide involved in the regulation of cellular metabolism, insulin sensitivity, and energy balance. It is encoded within mitochondrial DNA and has gained significant research attention for its potential role in metabolic health, exercise performance, and age-related metabolic decline.
Injectable MOTS-C (subcutaneous) to rapidly increase systemic peptide availability.
This protocol supports metabolic regulation and mitochondrial function from multiple biological angles.
Key Benefits:
- Metabolic Regulation – Supports pathways involved in glucose metabolism and insulin sensitivity
- Energy Production – Enhances mitochondrial function and cellular energy utilization
- Exercise Performance – Studied for its role in improving endurance and metabolic flexibility
- Fat Metabolism – May support lipid utilization and metabolic efficiency
- Longevity Research – Investigated for its involvement in age-related metabolic resilience
Product Information
Product Name: MOTS-C
Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular Weight: 2174.6 g/mol
CAS Number: Not officially assigned
Synonym: Mitochondrial Open Reading Frame of the 12S rRNA-c, MOTS-c Peptide, Mitochondrial-Derived Peptide MOTS-C
Intro
MOTS-C is a naturally occurring peptide encoded by mitochondrial DNA and discovered as part of a group of mitochondrial-derived peptides involved in metabolic regulation. Unlike most peptides encoded by nuclear DNA, MOTS-C originates from the mitochondria, the energy-producing structures within cells.
Research has shown that MOTS-C plays a role in regulating metabolic pathways related to glucose uptake, insulin sensitivity, and energy balance. It appears to activate signaling pathways associated with metabolic stress responses and cellular energy regulation.
MOTS-C levels may decline with age, and alterations in its signaling have been associated with metabolic dysfunction and reduced metabolic flexibility.
Because of its influence on mitochondrial signaling and metabolic pathways, MOTS-C has become an important focus in research investigating metabolic disorders, exercise physiology, and longevity biology.
The Science
MOTS-C functions as a mitochondrial-derived signaling peptide that regulates metabolic homeostasis. One of its primary mechanisms involves activation of AMP-activated protein kinase (AMPK), a key cellular energy sensor responsible for maintaining metabolic balance.
Activation of AMPK promotes glucose uptake, enhances fatty acid oxidation, and improves cellular energy efficiency. Through this pathway, MOTS-C helps cells adapt to metabolic stress and optimize energy utilization.
MOTS-C has also been shown to influence nuclear gene expression by translocating from the mitochondria to the nucleus under conditions of metabolic stress. This signaling activity allows the peptide to regulate genes involved in metabolism, inflammation, and cellular stress responses.
Additionally, research suggests that MOTS-C may improve insulin sensitivity and support metabolic flexibility, allowing the body to efficiently switch between carbohydrate and fat utilization for energy.
Through these mechanisms, MOTS-C plays a role in coordinating mitochondrial signaling with systemic metabolic regulation.
Dosing Protocol
Injectable MOTS-C (Subcutaneous)
Concentration: Approx. 30 mg per vial (standard)
Dosage: 5–10 mg per administration
Administration: Subcutaneously into the abdomen
Duration: 2–3 injections per week for 3–4 weeks
Buy MOTS-C at Platinum Research Compounds
At Platinum Research Compounds, we provide research-grade MOTS-C formulated to meet strict purity and stability standards. Our peptide formulations are designed for researchers, clinicians, and advanced users studying metabolic peptides and mitochondrial signaling compounds.
From secure packaging to responsive support, our commitment to quality and integrity makes us a trusted source for research peptides in Australia.
Product FAQ
What is MOTS-C used for?
MOTS-C is studied for its role in regulating metabolism, improving insulin sensitivity, and supporting mitochondrial signaling.
What conditions is it being studied for?
Research has explored MOTS-C in metabolic disorders, insulin resistance, obesity, exercise physiology, and aging-related metabolic decline.
Is it safe?
Early research suggests MOTS-C has shown promising safety profiles in controlled studies. However, it should only be used in approved research or supervised settings.
Can MOTS-C improve exercise performance?
Research suggests MOTS-C may enhance metabolic flexibility and endurance by supporting mitochondrial energy metabolism.
