LGD-4033 can even grow and strengthen both muscle and bone with each use, helping your body perform at its peak without limitation. Crucially, it does this without increasing fat deposits or showing signs of any other tissue affects within the body. Studies have also proven the SARM can heal injury with regular use, making it extremely popular in the performance enhancing world.
- Helps to build lean muscle
- Safer than testosterone
- Grows and strengthens bones
- No adverse effects on fat or tissue
- Aids in injury repair
- Speeds up recovery time
- Non-toxic & orally administered
Product Name: LGD-4033, VK5211, Ligandrol.
Molecular Formula: C14H12F6N2O
What is it?
LGD-4033 (VK5211, Ligandrol) is a brand new selective androgen receptor modulator (SARM) that targets the androgen receptors in the muscles resulting in lean muscle growth and increased strength.
LGD-4033 is a non-toxic oral compound with a very strong effectiveness profile and highly promising clinical trial results so far.
This compound results in significant muscle growth and is similar in effect to anabolic steroids without all the nasty side effects. It is a great way to bulk up muscle mass while avoiding the dangerous aspects of steroid use.
Mechanism of action?
It is a non-steroidal, orally administered SARM which binds to the androgen receptor with a high affinity and high selectivity. It demonstrates anabolic activity in muscles as well as anti-resorptive and anabolic activity in bones meaning that it grows and strengthens both of these tissues without adversely affecting surrounding tissue. It exhibits a high selectivity for muscle and bone tissue versus prostate and sebaceous glands unlike testosterone so in many cases this compound produces the therapeutic benefits of testosterone with improved safety and tolerability due to this tissue-selective mechanism.
It is currently under development as a treatment for muscle wasting and osteoporosis through the company Viking Therapeutics because of its potential to increase muscle gain and bone strength.
Oral administration of the drug in Macaca fascicularis at daily doses varying from 0 to 75 mg/kg over 13 weeks demonstrated significant body weight gain in both male and female subjects.
In a Phase I clinical trial of 76 adult male humans in which the dose size was varied, a dose-dependent increase in lean body mass was observed with no significant adverse events over the 21 days of the trial. This means that the subjects gained lean muscle without experiencing any negative symptoms and speaks to the amazing potential of this compound to help build body mass.
Hemoglobin, prostate-specific antigen, aspartate aminotransferase, alanine aminotransferase, and QT intervals did not change significantly at any dose in this trial and lean body mass increased dose dependently, but fat mass did not change significantly meaning that the compound builds muscle and bone without also increasing fat deposits.
Hormone levels and lipid levels all returned to baseline after treatment discontinuation.
The Phase 2 clinical trial currently underway consists of 120 patients recovering from hip fracture surgery. Improved lean body mass is the primary endpoint of this study and it is still ongoing but this compound has the potential to radically improve the quality of patient lives and increase the speed of recovery.
It shows anabolic activity in the bones and muscles instead of harmfully affecting the prostate and sebaceous glands which usually happens when using steroids.
Overall this compound has amazing potential to aid in the development of muscle tissue and bone strength without increasing fat deposits or affecting other tissues in the body. It has the added advantage of aiding the healing process after muscle and bone injury and is a compound with staggering clinical potential.
This compound provides most of the benefits of a typical anabolic steroid without the side effects and long recovery times.
LGD-4033, also known as Ligandrol, is a selective androgen receptor modulator (SARM). It was initially developed to treat muscle wasting diseases and prevent osteoporosis; however, it has since been explored for its potential in helping with bodybuilding, specifically aiding muscle growth, fat loss, and improved strength.
The use of LGD-4033 can promote lean body mass and reduce fat but also increase strength, endurance, and bone mineral density. Its effectiveness in combating osteoporosis can be seen through its ability to improve the overall condition of bones by increasing their mineral content.
LGD-4033 targets the androgen receptors in the body and activates them to promote the growth and maintenance of muscle tissue. It also helps reduce fat and increase bone density, making it a versatile supplement for those looking to improve their physical performance.
Clinical studies showed that LGD-4033 could significantly boost anabolic activity in muscles and bones while drastically reducing muscle loss and bone deterioration among those with muscular dystrophy, osteoporosis, the elderly, or cancer. Furthermore, another research found LGD-4033 to be safe and have a favorable pharmacokinetic profile.
LGD-4033 is often mixed with other SARMs such as MK-677, Ostarine, and RAD 140. These SARMs have demonstrated similar results as LGD-4033 in improving muscle mass and strength but can offer additional benefits such as improved joint function and increased fat loss. One should always consult professionals before taking any SARM combination, as the effects of these different SARMs can vary.